Why psychedelics make the mundane profoundHow our built-in novelty detector gets hijacked

From the show

Psychedelic Mind

Psychedelics fundamentally alter how we process everyday sights and sounds. By increasing the sensitivity of the locus coeruleus—our primary source of norepinephrine—these substances cause familiar objects to trigger the same arousal as entirely new experiences. This biological mechanism explains the deep fascination often felt during a trip.