How Psilocybin Rewires Depression TreatmentHealing by facing pain, not turning it down

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Psychedelic Mind

Neuroimaging reveals a stark mechanism difference between standard antidepressants and psychedelic therapy. While SSRIs often blunt the brain's response to negative emotions, psilocybin appears to heighten emotional reactivity. This suggests true healing may come from confronting difficult feelings rather than suppressing the brain's threat detection system.