Salvia: When Reality FoldsWhy the kappa-opioid system breaks physics

From the show

Psychedelic Mind

Most psychedelics mimic serotonin to expand connection, but Salvinorin A targets the brain’s kappa-opioid receptors to disrupt proprioception and self-embodiment. This unique pharmacological action explains common reports of feeling gravity shifts, becoming inanimate objects, or perceiving reality as a conveyor belt. It offers a stark contrast to classical hallucinogens by activating the body's anti-reward system.