The LSD Molecular TrapWhy acid trips outlast the drug's presence in blood

From the show

Psychedelic Mind

Current research explains why LSD effects persist for 12 hours even after the chemical leaves the bloodstream. Crystal structure analysis reveals that the 5-HT2A receptor forms a "lid" over the molecule, physically trapping it in place. We examine how this unique binding kinetics drives the drug's extreme potency and characteristic "waves" of intensity.